Development of a membrane-based Gi-CASE biosensor assay for profiling compounds at cannabinoid receptors
Introduction: The cannabinoid receptor (CBR) subtypes 1 (CB1R) and 2 (CB2R) are key components of the endocannabinoid system (ECS), playing a central role in the control of peripheral pain, inflammation and the immune response, with further roles in the endocrine regulation of food intake and energy...
Saved in:
Main Authors: | Morgan Scott-Dennis (Author), Fikri A. Rafani (Author), Yicheng Yi (Author), Themiya Perera (Author), Clare R. Harwood (Author), Wolfgang Guba (Author), Arne C. Rufer (Author), Uwe Grether (Author), Dmitry B. Veprintsev (Author), David A. Sykes (Author) |
---|---|
Format: | Book |
Published: |
Frontiers Media S.A.,
2023-08-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Large-Scale Production and Protein Engineering of G Protein-Coupled Receptors for Structural Studies
by: Dalibor eMilić, et al.
Published: (2015) -
Exploring the kinetic selectivity of drugs targeting the β1‐adrenoceptor
by: David A. Sykes, et al.
Published: (2022) -
Combined docking and machine learning identify key molecular determinants of ligand pharmacological activity on β2 adrenoceptor
by: Mireia Jiménez‐Rosés, et al.
Published: (2022) -
A Modified Cell-Penetrating Peptide Enhances Insulin and Oxytocin Delivery across an RPMI 2650 Nasal Epithelial Cell Barrier In Vitro
by: Sara Wong, et al.
Published: (2024) -
Stabilization of G protein-coupled receptors by point mutations
by: Franziska eHeydenreich, et al.
Published: (2015)