THE TRAFFICKING OF THE WATER CHANNEL AQUAPORIN-2 IN RENAL PRINCIPAL CELLS - A POTENTIAL TARGET FOR PHARMACOLOGICAL INTERVENTION IN CARDIOVASCULAR DISEASES

• 主要な著者: Tanja eVukicevic (著者), Maike eSchulz (著者), Dörte eFaust (著者), Enno eKlussmann (著者)
• フォーマット: 図書
• 出版事項: Frontiers Media S.A., 2016-02-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Arginine-vasopressin (AVP) stimulates the redistribution of water channels, aquaporin-2 (AQP2) from intracellular vesicles into the plasma membrane of renal collecting duct principal cells. By this AVP directs 10 % of the water reabsorption from the 170 L of primary urine that the human kidneys prod...