The Ankylosing Spondylitis-Associated HLA-B*2705 Presents a B*0702-Restricted EBV Epitope and Sustains the Clonal Amplification of Cytotoxic T Cells in Patients

• Main Authors: Valentina Tedeschi (Author), Carolina Vitulano (Author), Alberto Cauli (Author), Fabiana Paladini (Author), Matteo Piga (Author), Alessandro Mathieu (Author), Rosa Sorrentino (Author), Maria Teresa Fiorillo (Author)
• Format: Book
• Published: BMC, 2016-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract HLA-B*27 is strongly associated with an inflammatory autoimmune disorder, the Ankylosing Spondylitis (AS) and plays a protective role in viral infections. The two aspects might be linked. In this work, we compared in B*2705/B*07 positive patients with AS, the CD8+ T cell responses to two im...