Pathophysiology of Post Transplant Hypertension in Kidney Transplant: Focus on Calcineurin Inhibitors Induced Oxidative Stress and Renal Sodium Retention and Implications with RhoA/Rho Kinase Pathway

• Main Authors: Lorenzo A. Calò (Author), Verdiana Ravarotto (Author), Francesca Simioni (Author), Elena Naso (Author), Francesco Marchini (Author), Luciana Bonfante (Author), Lucrezia Furian (Author), Paolo Rigotti (Author)
• Format: Book
• Published: Karger Publishers, 2017-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Post-transplant hypertension is a common occurrence during treatment with calcineurin inhibitors (CNIs) in kidney transplant population. The pathogenesis of vasoconstriction induced by CNIs involves vascular tone alterations and kidney sodium transport regulation. Among the factors involved a key ro...