Modulatory Effect of 4-(methylthio)butyl Isothiocyanate Isolated From Eruca Sativa Thell. on DMBA Induced Overexpression of Hypoxia and Glycolytic Pathway in Sprague-Dawley Female Rats

• Main Authors: Davinder Singh (Author), Sharad Thakur (Author), Drishtant Singh (Author), Harpal Singh Buttar (Author), Balbir Singh (Author), Saroj Arora (Author)
• Format: Bog
• Udgivet: Frontiers Media S.A., 2021-08-01T00:00:00Z.
• Fag: article
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4-(methylthio)butyl isothiocyanate (4-MTBITC) is a hydrolytic product from the plant Eruca sativa Thell. In the present study, we explored the anti-cancer effect of 4-MTBITC against 7,12-dimethylbenz [a] anthracene (DMBA) induced breast cancer. Hypoxic conditions were developed using a single dose o...