H19X‐encoded miR‐322(424)/miR‐503 regulates muscle mass by targeting translation initiation factors

• Main Authors: Rui Liang (Author), Xiaopeng Shen (Author), Fan Wang (Author), Xin Wang (Author), Alex DesJarlais (Author), Anam Syed (Author), Raymond Saba (Author), Zhi Tan (Author), Fang Yu (Author), Xuan Ji (Author), Shreesti Shrestha (Author), Yinghong Ren (Author), Jin Yang (Author), Yoonjung Park (Author), Robert J. Schwartz (Author), Benjamin Soibam (Author), Bradley K. McConnell (Author), M. David Stewart (Author), Ashok Kumar (Author), Yu Liu (Author)
• Format: Book
• Published: Wiley, 2021-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Skeletal muscle atrophy is a debilitating complication of many chronic diseases, disuse conditions, and ageing. Genome‐wide gene expression analyses have identified that elevated levels of microRNAs encoded by the H19X locus are among the most significant changes in skeletal musc...