Adipocytes fail to maintain cellular identity during obesity due to reduced PPARγ activity and elevated TGFβ-SMAD signaling
Objective: Obesity due to overnutrition causes adipose tissue dysfunction, which is a critical pathological step on the road to type 2 diabetes (T2D) and other metabolic disorders. In this study, we conducted an unbiased investigation into the fundamental molecular mechanisms by which adipocytes tra...
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| Main Authors: | , , , , , , , |
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| Format: | Book |
| Published: |
Elsevier,
2020-12-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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