Gypenosides ameliorate ductular reaction and liver fibrosis via inhibition of hedgehog signaling

• Main Authors: Yonghong Hu (Author), Xiaoli He (Author), Xiaoxi Zhou (Author), Yue Liang (Author), Yadong Fu (Author), Linzhang Zhang (Author), Jing Fang (Author), Wei Liu (Author), Gaofeng Chen (Author), Yongping Mu (Author), Hua Zhang (Author), Hong Cai (Author), Chenghai Liu (Author), Ping Liu (Author), Jiamei Chen (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Backgroud and aims: Ductular reaction (DR) is a common pathological change and thought to have a key role in the pathogenesis and progression of liver fibrosis. Our previous study reported Gypenosides (GPs) ameliorated liver fibrosis, however, the anti-fibrotic mechanisms of GPs are still unclear.Me...