Semi-PBPK Modeling and Simulation to Evaluate the Local and Systemic Pharmacokinetics of OC-01(Varenicline) Nasal Spray
This study aimed to build a nasal semi-physiologically based pharmacokinetic (PBPK) model to predict the intranasal pharmacokinetic (PK) of the OC-01(varenicline) nasal spray and accelerate the development of this drug. Based on the physiology of the human upper respiratory system, the semi-PBPK mod...
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Main Authors: | , , , , , , , , |
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Format: | Book |
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Frontiers Media S.A.,
2022-07-01T00:00:00Z.
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A1234.567 |
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Copy 1 | Available |