Discovery of Highly Trimethoprim-Resistant DfrB Dihydrofolate Reductases in Diverse Environmental Settings Suggests an Evolutionary Advantage Unrelated to Antibiotic Resistance

• Asıl Yazarlar: Stella Cellier-Goetghebeur (Yazar), Kiana Lafontaine (Yazar), Claudèle Lemay- (Yazar), Princesse Tsamo (Yazar), Alexis Bonneau-Burke (Yazar), Janine N. Copp (Yazar), Joelle N. Pelletier (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: MDPI AG, 2022-12-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Type B dihydrofolate reductases (DfrB) are intrinsically highly resistant to the widely used antibiotic trimethoprim, posing a threat to global public health. The ten known DfrB family members have been strongly associated with genetic material related to the application of antibiotics. Several <...