Improving the efficacy for meropenem therapy requires a high probability of target attainment in critically ill infants and children

• Main Authors: Zeming Wang (Author), Jing Bi (Author), Dianping You (Author), Yu Tang (Author), Gang Liu (Author), Jinqian Yu (Author), Zhipeng Jin (Author), Tingting Jiang (Author), Xue Tian (Author), Hui Qi (Author), Lei Dong (Author), Lili Dong (Author), Qunqun Zhang (Author), Wei Zhao (Author), Adong Shen (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Probability of target attainment is the key factor influencing the outcome of meropenem therapy. The objective of the present study was to evaluate the relationship between the time in which the plasma free concentration of meropenem exceeds the minimum inhibitory concentration of pathogens (fT>M...