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Pharmacological Profiles of the Novel Analgesic M58996 in Rat Models of Persistent and Neuropathic Pain

We investigated the effects of 4-(N-{1-[2-(4-cyanophenyl)ethyl]-4-hydroxypiperidin-4-ylmethyl}-N-methylamino)benzoic acid monohydrochloride (M58996), a novel analgesic, on persistent and neuropathic pain in rats. In the formalin test, oral M58996 (0.3 - 10 mg/kg) reduced nociceptive behaviors only i...

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Main Authors: Yasushige Akada (Author), Reiko Mori (Author), Kazuyuki Matsuura (Author), Kazuhiro Suzuki (Author), Kazuo Kato (Author), Masatsugu Kamiya (Author), Hiroyasu Naba (Author), Misao Kurokawa (Author), Takuo Ogihara (Author), Yutaka Kato (Author), Fumiaki Yamasaki (Author), Ichiro Yamamoto (Author)
Format: Book
Published: Elsevier, 2006-01-01T00:00:00Z.
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