Exosome-mediated transfer of CD44 from high-metastatic ovarian cancer cells promotes migration and invasion of low-metastatic ovarian cancer cells

• Main Authors: Xiameng Shen (Author), Conghui Wang (Author), Huihui Zhu (Author), Yaping Wang (Author), Xinyu Wang (Author), Xiaodong Cheng (Author), Wanzhong Ge (Author), Weiguo Lu (Author)
• Format: Book
• Published: BMC, 2021-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Objective To investigate the detailed roles and mechanisms of tumor-derived exosomes in progression and metastasis of ovarian cancer in vitro. Methods Exosomes were isolated by differential centrifugation method; the morphology, size and biological markers of exosomes were separately define...