Evaluation of a Meropenem and Piperacillin Monitoring Program in Intensive Care Unit Patients Calls for the Regular Assessment of Empirical Targets and Easy-to-Use Dosing Decision Tools

• Main Authors: Ferdinand Anton Weinelt (Author), Miriam Songa Stegemann (Author), Anja Theloe (Author), Frieder Pfäfflin (Author), Stephan Achterberg (Author), Franz Weber (Author), Lucas Dübel (Author), Agata Mikolajewska (Author), Alexander Uhrig (Author), Peggy Kiessling (Author), Wilhelm Huisinga (Author), Robin Michelet (Author), Stefanie Hennig (Author), Charlotte Kloft (Author)
• Format: Book
• Published: MDPI AG, 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The drug concentrations targeted in meropenem and piperacillin/tazobactam therapy also depend on the susceptibility of the pathogen. Yet, the pathogen is often unknown, and antibiotic therapy is guided by empirical targets. To reliably achieve the targeted concentrations, dosing needs to be adjusted...