Neuroserpin Is Strongly Expressed in the Developing and Adult Mouse Neocortex but Its Absence Does Not Perturb Cortical Lamination and Synaptic Proteome

• Main Authors: Dilara Kement (Author), Rebecca Reumann (Author), Katrin Schostak (Author), Hannah Voß (Author), Sara Douceau (Author), Matthias Dottermusch (Author), Michaela Schweizer (Author), Hartmut Schlüter (Author), Denis Vivien (Author), Markus Glatzel (Author), Giovanna Galliciotti (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Neuroserpin is a serine protease inhibitor that regulates the activity of tissue-type plasminogen activator (tPA) in the nervous system. Neuroserpin is strongly expressed during nervous system development as well as during adulthood, when it is predominantly found in regions eliciting synaptic plast...