Anticancer and Structure Activity Relationship of Non-Symmetrical Choline Kinase Inhibitors

• Main Authors: Santiago Schiaffino-Ortega (Author), Elena Mariotto (Author), Pilar María Luque-Navarro (Author), María Kimatrai-Salvador (Author), Pablo Rios-Marco (Author), Ramon Hurtado-Guerrero (Author), Carmen Marco (Author), María Paz Carrasco-Jimenez (Author), Giampietro Viola (Author), Luisa Carlota López-Cara (Author)
• Format: Book
• Published: MDPI AG, 2021-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Choline kinase inhibitors are an outstanding class of cytotoxic compounds useful for the treatment of different forms of cancer since aberrant choline metabolism is a feature of neoplastic cells. Here, we present the most in-depth structure-activity relationship studies of an interesting series of n...