pH-triggered dynamic erosive small molecule chlorambucil nano-prodrugs mediate robust oral chemotherapy

• Main Authors: Xin Liu (Author), Zhexiang Wang (Author), Xiaodie Ren (Author), Xinyang Chen (Author), Jinjin Tao (Author), Yuanhui Guan (Author), Xuefeng Yang (Author), Rupei Tang (Author), Guoqing Yan (Author)
• Format: Book
• Published: Elsevier, 2023-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Currently, the dynamic erosive small molecule nano-prodrug is of great demand for oral chemotherapy, owing to its precise structure, high drug loading and improved oral bioavailability via overcoming various physiologic barriers in gastrointestinal tract, blood circulation and tumor tissues compared...