hucMSC-Ex Alleviates IBD-Associated Intestinal Fibrosis by Inhibiting ERK Phosphorylation in Intestinal Fibroblasts

• Main Authors: Yifei Wang (Author), Yaqin Zhang (Author), Bing Lu (Author), Jianbo Xi (Author), Dickson Kofi Wiredu Ocansey (Author), Fei Mao (Author), Donglin Hao (Author), Yongmin Yan (Author)
• Format: Book
• Published: Hindawi Limited, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background. Intestinal fibrosis, one of the complications of inflammatory bowel disease (IBD), is associated with fistula and intestinal stricture formation. There are currently no treatments for fibrosis. Mesenchymal stem cell-derived exosomes have been proven to exert inhibitory and reversal effec...