Implication of extracellular zinc exclusion by recombinant human calprotectin (MRP8 and MRP14) from target cells in its apoptosis-inducing activity

• Главные авторы: Satoru Yui (Автор), Yuichi Nakatani (Автор), Michael J. Hunter (Автор), Walter J. Chazin (Автор), Masatoshi Yamazaki (Автор)
• Формат: ‌
• Опубликовано: Hindawi Limited, 2002-01-01T00:00:00Z.
• Предметы: article
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Background: Calprotectin is a calcium-binding and zinc-binding protein complex that is abundant in the cytosol of neutrophils. This factor is composed of 8 and 14 kDa subunits, which have also been termed migration inhibitory factor-related proteins MRP8 and MRP14. We previously reported that rat ca...