Bayesian hierarchical model-based network meta-analysis to overcome survival extrapolation challenges caused by data immaturity

• Päätekijät: Bart Heeg (Tekijä), Andre Verhoek (Tekijä), Gabriel Tremblay (Tekijä), Ofir Harari (Tekijä), Mohsen Soltanifar (Tekijä), Haitao Chu (Tekijä), Satrajit Roychoudhury (Tekijä), Joseph C Cappelleri (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Becaris Publishing Limited, 2023-01-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Aim: This research evaluated standard Weibull mixture cure (WMC) network meta-analysis (NMA) with Bayesian hierarchical (BH)WMCNMAto inform long-term survival of therapies. Materials & methods: Four trials in previously treated metastatic non-small-cell lung cancer with PD-L1 >1% were used co...