A mechanism‐based pharmacokinetic model of remdesivir leveraging interspecies scaling to simulate COVID‐19 treatment in humans

A mechanism‐based pharmacokinetic model of remdesivir leveraging interspecies scaling to simulate COVID‐19 treatment in humans

Abstract The severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) outbreak initiated the global coronavirus disease 2019 (COVID‐19) pandemic resulting in 42.9 million confirmed infections and > 1.1 million deaths worldwide as of October 26, 2020. Remdesivir is a broad‐spectrum nucleotide...

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Main Authors: Patrick O. Hanafin (Author), Brian Jermain (Author), Anthony J. Hickey (Author), Alexander V. Kabanov (Author), Angela DM. Kashuba (Author), Timothy P. Sheahan (Author), Gauri G. Rao (Author)
Format: Book
Published: Wiley, 2021-02-01T00:00:00Z.
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