Recalcitrant Issues and New Frontiers in Nano-Pharmacology

Packaging of old pharma drugs into new packaging "nanoparticles" is called nano-pharmacology and the products are called nano-based drugs. The inception of nano-pharmacology research and development (R&D) is marked by the approval of the first nano-based drug Doxil® in 1995 by the Food...

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Bibliographic Details
Main Authors: Vinay Bhardwaj (Author), Ajeet Kaushik (Author), Ziad M. Khatib (Author), Madhavan Nair (Author), Anthony J. McGoron (Author)
Format: Book
Published: Frontiers Media S.A., 2019-11-01T00:00:00Z.
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Summary:Packaging of old pharma drugs into new packaging "nanoparticles" is called nano-pharmacology and the products are called nano-based drugs. The inception of nano-pharmacology research and development (R&D) is marked by the approval of the first nano-based drug Doxil® in 1995 by the Food and Drug Administration. However, even after more than two decades, today, there are only ∼20 nano-based drugs in the market to treat cancers and brain diseases. In this article we share the perspectives of nanotechnology scientists, engineers, and clinicians on the roadblocks in nano-pharmacology R&D. Also, we share our opinion on new frontiers in the field of nano-pharmacology R&D that may allow rapid and efficient transfer of nano-pharma technologies from R&D to market.
Item Description:1663-9812
10.3389/fphar.2019.01369