Suppression of Choroidal Neovascularization and Fibrosis by a Novel RNAi Therapeutic Agent against (Pro)renin Receptor

• Prif Awduron: Ye Liu (Awdur), Atsuhiro Kanda (Awdur), Di Wu (Awdur), Erdal Tan Ishizuka (Awdur), Satoru Kase (Awdur), Kousuke Noda (Awdur), Atsuhiro Ichihara (Awdur), Susumu Ishida (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: Elsevier, 2019-09-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

The receptor-associated prorenin system refers to the pathogenic mechanism whereby prorenin binding to (pro)renin receptor [(P)RR] dually activates the tissue renin-angiotensin system (RAS) and RAS-independent signaling, and its activation contributes to the molecular pathogenesis of various ocular...