NTRK fusions in osteosarcoma are rare and non‐functional events

NTRK fusions in osteosarcoma are rare and non‐functional events

Abstract Neurotrophic tyrosine receptor kinase (NTRK) fusions are promising molecular targets that have been described in a broad range of malignant tumours. Fusions commonly lead to the expression of chimeric proteins with constitutive tyrosine kinase activation that drives tumorigenesis. Despite a...

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Main Authors: Baptiste Ameline (Author), Karim H Saba (Author), Michal Kovac (Author), Linda Magnusson (Author), Olaf Witt (Author), Stefan Bielack (Author), Michaela Nathrath (Author), Karolin H Nord (Author), Daniel Baumhoer (Author)
Format: Book
Published: Wiley, 2020-04-01T00:00:00Z.
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3rd Floor Main Library

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