HMG-CoA Reductase Inhibitor Statins Activate the Transcriptional Activity of p53 by Regulating the Expression of TAZ

• मुख्य लेखकों: Chiharu Miyajima (लेखक), Yurika Hayakawa (लेखक), Yasumichi Inoue (लेखक), Mai Nagasaka (लेखक), Hidetoshi Hayashi (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2022-08-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Transcriptional coactivator with PDZ-binding motif (TAZ) is a downstream transcriptional regulator of the Hippo pathway that controls cell growth and differentiation. The aberrant activation of TAZ correlates with a poor prognosis in human cancers, such as breast and colon cancers. We previously dem...