Protective Effects of Silymarin on Gentamicin-Induced Nephrotoxicity in Infectious Patients: A Randomized Double Blinded Placebo-Controlled Clinical Trial

• Main Authors: Motahareh Mahi-birjand (Author), Iman Karimzadeh (Author), Asghar Zarban (Author), Meghdad Abdollahpour-Alitappeh (Author), Seyed Alireza Saadatjoo (Author), Masood Ziaee (Author)
• Format: Book
• Published: Tabriz University of Medical Sciences, 2020-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Nephrotoxicity is one of the most important side effects of gentamicin (GEN). Accumulating evidence demonstrated the crucial roles of antioxidant compounds in the reduction of GEN-induced renal injuries. Silymarin (SM),an antioxidant agent,was demonstrated toimprove GEN-induced kidney da...