Easy-to-Use HPLC Method to Measure Intracellular Ascorbic Acid Levels in Human Peripheral Blood Mononuclear Cells and in Plasma

• Main Authors: Gwendolyn van Gorkom (Author), Birgit Gijsbers (Author), Erik-Jan Ververs (Author), Ahmed El Molla (Author), Cindy Sarodnik (Author), Celine Riess (Author), Will Wodzig (Author), Gerard Bos (Author), Catharina Van Elssen (Author)
• Format: Book
• Published: MDPI AG, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Given the growing interest in ascorbic acid (AA), there is a need for a reliable and reproducible method to measure AA status in the human body. Serum AA concentrations do not correlate well with tissue levels, but AA levels in leukocytes do. However, a standard method for clinical application is la...