HMGB1 and Toll-like receptors: potential therapeutic targets in autoimmune diseases
Abstract HMGB1, a nucleoprotein, is expressed in almost all eukaryotic cells. During cell activation and cell death, HMGB1 can function as an alarm protein (alarmin) or damage-associated molecular pattern (DAMP) and mediate early inflammatory and immune response when it is translocated to the extrac...
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2023-09-01T00:00:00Z.
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