Hypoxic ucMSC-secreted exosomal miR-125b promotes endothelial cell survival and migration during wound healing by targeting TP53INP1

• Principais autores: Xiao-Fei Zhang (Autor), Ting Wang (Autor), Zi-Xuan Wang (Autor), Kun-Peng Huang (Autor), Yun-Wei Zhang (Autor), Guo-Liang Wang (Autor), Hong-Ji Zhang (Autor), Zi-Han Chen (Autor), Chang-Yan Wang (Autor), Jin-Xiang Zhang (Autor), Hui Wang (Autor)
• Formato: Livro
• Publicado em: Elsevier, 2021-12-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

A hypoxic microenvironment is a common feature of skin wounds. Our previous study demonstrated that three-dimensional coculture of umbilical cord-derived mesenchymal stem cells (ucMSCs) and endothelial cells facilitates cell communication and host integration in skin tissue engineering. Here, we aim...