Hypoxic ucMSC-secreted exosomal miR-125b promotes endothelial cell survival and migration during wound healing by targeting TP53INP1

• Main Authors: Xiao-Fei Zhang (Author), Ting Wang (Author), Zi-Xuan Wang (Author), Kun-Peng Huang (Author), Yun-Wei Zhang (Author), Guo-Liang Wang (Author), Hong-Ji Zhang (Author), Zi-Han Chen (Author), Chang-Yan Wang (Author), Jin-Xiang Zhang (Author), Hui Wang (Author)
• Format: Book
• Published: Elsevier, 2021-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A hypoxic microenvironment is a common feature of skin wounds. Our previous study demonstrated that three-dimensional coculture of umbilical cord-derived mesenchymal stem cells (ucMSCs) and endothelial cells facilitates cell communication and host integration in skin tissue engineering. Here, we aim...