Establishment of a drug evaluation model against light-induced retinal degeneration using adult pigmented zebrafish

• Main Authors: Yuichi Saito (Author), Kazuhiro Tsuruma (Author), Masamitsu Shimazawa (Author), Yuhei Nishimura (Author), Toshio Tanaka (Author), Hideaki Hara (Author)
• Format: Book
• Published: Elsevier, 2016-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Age-related macular degeneration (AMD) is a major cause of irreversible loss of central vision in the elderly. Zebrafish is an attractive animal model in some respects, lower cost, smaller housing facilities and easier genetic manipulation compared to rodents. The present study aimed to establish a...