Efficient analysis of adverse drug events and toxicological mechanisms of newly marketed drugs by integrating pharmacovigilance and network toxicology: selumetinib as an example

• Main Authors: Rui Xiong (Author), Jing Lei (Author), Lu Wang (Author), Shipeng Zhang (Author), Hengxu Liu (Author), Hongping Wang (Author), Tao Liu (Author), Xiaodan Lai (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

ObjectiveTo integrate pharmacovigilance and network toxicology methods to explore the potential adverse drug events (ADEs) and toxic mechanisms of selumetinib, and to provide a reference for quickly understanding the safety and toxicological mechanisms of newly marketed drugs.MethodsTaking selumetin...