Synthesis and Antimalarial Evaluation of New 1,3,5-<i>tris</i>[(4-(Substituted-aminomethyl)phenyl)methyl]benzene Derivatives: A Novel Alternative Antiparasitic Scaffold

• Main Authors: Sandra Albenque-Rubio (Author), Jean Guillon (Author), Anita Cohen (Author), Patrice Agnamey (Author), Solène Savrimoutou (Author), Stéphane Moreau (Author), Jean-Louis Mergny (Author), Luisa Ronga (Author), Ioannis Kanavos (Author), Serge Moukha (Author), Pascale Dozolme (Author), Pascal Sonnet (Author)
• Format: Book
• Published: MDPI AG, 2023-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A series of new 1,3,5-<i>tris</i>[(4-(substituted-aminomethyl)phenyl)methyl]benzene compounds were designed, synthesized, and evaluated <i>in vitro</i> against two parasites (<i>Plasmodium falciparum</i> and <i>Leishmania donovani</i>). The biological...