Development of a novel, high-affinity ssDNA trypsin inhibitor

• Main Authors: Stanislaw Malicki (Author), Miroslaw Ksiazek (Author), Pawel Majewski (Author), Aleksandra Pecak (Author), Piotr Mydel (Author), Przemyslaw Grudnik (Author), Grzegorz Dubin (Author)
• Format: Book
• Published: Taylor & Francis Group, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Inhibitors of serine proteases are not only extremely useful in the basic research but are also applied extensively in clinical settings. Using Systematic Evolution of Ligands by Exponential Enrichment (SELEX) approach we developed a family of novel, single-stranded DNA aptamers capable of specific...