Replenishable prevascularized cell encapsulation devices increase graft survival and function in the subcutaneous space

• Main Authors: Gauree S. Chendke (Author), Bhushan N. Kharbikar (Author), Sudipta Ashe (Author), Gaetano Faleo (Author), Julie B. Sneddon (Author), Qizhi Tang (Author), Matthias Hebrok (Author), Tejal A. Desai (Author)
• Format: Book
• Published: Wiley, 2023-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Beta cell replacement therapy (BCRT) for patients with type 1 diabetes (T1D) improves blood glucose regulation by replenishing the endogenous beta cells destroyed by autoimmune attack. Several limitations, including immune isolation, prevent this therapy from reaching its full potential. Ce...