LC-HRMS determination of piperine on rat dried blood spots: A pharmacokinetic study

• Main Authors: Bokka Ramesh (Author), P. Rajesh Rao Vadaparthi (Author), Genji Sukumar (Author), Nemali Manjula (Author), Katragadda Suresh Babu (Author), Potturi Sita Devi (Author)
• Format: Book
• Published: Elsevier, 2016-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A liquid chromatography-high resolution mass spectrometry (LC-HRMS) method was developed and validated for the determination of piperine (PPR) on dried blood spots (DBS). DBS samples were prepared by spiking the whole blood with analyte to produce 30 µL of blood spots on specimen collection cards. C...