OP3‐4 peptide sustained‐release hydrogel inhibits osteoclast formation and promotes vascularization to promote bone regeneration in a rat femoral defect model

• Main Authors: Peng Luo (Author), Jiarui Fang (Author), Dazhi Yang (Author), Lan Yu (Author), Houqing Chen (Author), Changging Jiang (Author), Rui Guo (Author), Tao Zhu (Author), Shuo Tang (Author)
• Format: Book
• Published: Wiley, 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Bone injury caused changes to surrounding tissues, leading to a large number of osteoclasts appeared to clear the damaged bone tissue before bone regeneration. However, overactive osteoclasts will inhibit bone formation. In this study, we prepared methacrylylated gelatin (GelMA)‐based hydro...