The Effect of In Vitro Cultivation on the Transcriptome of Adult Brugia malayi.

• Main Authors: Cristina Ballesteros (Author), Lucienne Tritten (Author), Maeghan O'Neill (Author), Erica Burkman (Author), Weam I Zaky (Author), Jianguo Xia (Author), Andrew Moorhead (Author), Steven A Williams (Author), Timothy G Geary (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2016-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND:Filarial nematodes cause serious and debilitating infections in human populations of tropical countries, contributing to an entrenched cycle of poverty. Only one human filarial parasite, Brugia malayi, can be maintained in rodents in the laboratory setting. It has been a widely used model...