Isisekelo Sempilo study protocol for the effectiveness of HIV prevention embedded in sexual health with or without peer navigator support (Thetha Nami) to reduce prevalence of transmissible HIV amongst adolescents and young adults in rural KwaZulu-Natal: a 2 × 2 factorial randomised controlled trial

• Main Authors: Glory Chidumwa (Author), Natsayi Chimbindi (Author), Carina Herbst (Author), Nonhlanhla Okeselo (Author), Jaco Dreyer (Author), Thembelihle Zuma (Author), Theresa Smith (Author), Jean-Michel Molina (Author), Thandeka Khoza (Author), Nuala McGrath (Author), Janet Seeley (Author), Deenan Pillay (Author), Frank Tanser (Author), Guy Harling (Author), Lorraine Sherr (Author), Andrew Copas (Author), Kathy Baisley (Author), Maryam Shahmanesh (Author)
• Format: Book
• Published: BMC, 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Antiretroviral therapy (ART) through universal test and treat (UTT) and HIV pre-exposure prophylaxis (PrEP) substantially reduces HIV-related mortality, morbidity and incidence. Effective individual-level prevention modalities have not translated into population-level impact in s...