Genomic insights into the evolution and mechanisms of carbapenem-resistant hypervirulent Klebsiella pneumoniae co-harboring bla KPC and bla NDM: implications for public health threat mitigation

• Main Authors: Qian Wang (Author), Yue Liu (Author), Ran Chen (Author), Meng Zhang (Author), Zaifeng Si (Author), Yueling Wang (Author), Yan Jin (Author), Yuanyuan Bai (Author), Zhen Song (Author), Xinglun Lu (Author), Mingju Hao (Author), Yingying Hao (Author)
• Format: Book
• Published: BMC, 2024-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Carbapenem-resistant hypervirulent Klebsiella pneumoniae (CR-hvKP) co-producing bla KPC and bla NDM poses a serious threat to public health. This study aimed to investigate the mechanisms underlying the resistance and virulence of CR-hvKP isolates collected from a Chinese hospita...