A critical role for ChREBP-mediated FGF21 secretion in hepatic fructose metabolism

• প্রধান লেখক: ffolliott M. Fisher (Author), MiSung Kim (Author), Ludivine Doridot (Author), Jeremy C. Cunniff (Author), Thomas S. Parker (Author), Daniel M. Levine (Author), Marc K. Hellerstein (Author), Lisa C. Hudgins (Author), Eleftheria Maratos-Flier (Author), Mark A. Herman (Author)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Elsevier, 2017-01-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Objective: Increased fructose consumption is a contributor to the burgeoning epidemic of non-alcoholic fatty liver disease (NAFLD). Recent evidence indicates that the metabolic hormone FGF21 is regulated by fructose consumption in humans and rodents and may play a functional role in this nutritional...