Circulating Calreticulin Is Increased in Myelofibrosis: Correlation with Interleukin-6 Plasma Levels, Bone Marrow Fibrosis, and Splenomegaly

• Үндсэн зохиолчид: Daria Sollazzo (Зохиогч), Dorian Forte (Зохиогч), Nicola Polverelli (Зохиогч), Margherita Perricone (Зохиогч), Marco Romano (Зохиогч), Simona Luatti (Зохиогч), Nicola Vianelli (Зохиогч), Michele Cavo (Зохиогч), Francesca Palandri (Зохиогч), Lucia Catani (Зохиогч)
• Формат: Ном
• Хэвлэсэн: Hindawi Limited, 2016-01-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

Myelofibrosis (MF) is a clonal neoplasia of the hemopoietic stem/progenitor cells associated with genetic mutations in the Janus kinase 2 (JAK2), myeloproliferative leukemia virus oncogene (MPL), and calreticulin (CALR) genes. MF is also characterized by a state of chronic inflammation. Calreticulin...