Multiple 17-OHP Cutoff Co-Variates Fail to Improve 21-Hydroxylase Deficiency Screening Accuracy

• Autori principali: Preet K. Matharu (Autore), Patrice K. Held (Autore), David B. Allen (Autore)
• Natura: Libro
• Pubblicazione: MDPI AG, 2022-10-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

To improve the positive predictive value (PPV) of newborn screening for 21-hydroxylase deficiency (21OHD), co-variates have been used to modify 17-hydroxyprogesterone (17OHP) cutoffs. The objective of this study is to evaluate whether 17OHP screening cutoffs adjusted for both collection time (CT) an...