Ligand-based design, synthesis, computational insights, and in vitro studies of novel N-(5-Nitrothiazol-2-yl)-carboxamido derivatives as potent inhibitors of SARS-CoV-2 main protease

• Päätekijät: Mohamed Elagawany (Tekijä), Ayman Abo Elmaaty (Tekijä), Ahmed Mostafa (Tekijä), Noura M. Abo Shama (Tekijä), Eman Y. Santali (Tekijä), Bahaa Elgendy (Tekijä), Ahmed A. Al-Karmalawy (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Taylor & Francis Group, 2022-12-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

The global outbreak of the COVID-19 pandemic provokes scientists to make a prompt development of new effective therapeutic interventions for the battle against SARS-CoV-2. A new series of N-(5-nitrothiazol-2-yl)-carboxamido derivatives were designed and synthesised based on the structural optimisati...