Co-Treatment With Verapamil and Curcumin Attenuates the Behavioral Alterations Observed in Williams-Beuren Syndrome Mice by Regulation of MAPK Pathway and Microglia Overexpression

• Ngā kaituhi matua: Paula Ortiz-Romero (Author), Alejandro González-Simón (Author), Gustavo Egea (Author), Luis A. Pérez-Jurado (Author), Victoria Campuzano (Author)
• Hōputu: Pukapuka
• I whakaputaina: Frontiers Media S.A., 2021-08-01T00:00:00Z.
• Ngā marau: article
• Urunga tuihono: Connect to this object online.

Williams-Beuren syndrome (WBS) is a rare neurodevelopmental disorder characterized by a distinctive cognitive phenotype for which there are currently no effective treatments. We investigated the progression of behavioral deficits present in WBS complete deletion (CD) mice, after chronic treatment wi...