Mechanisms underlying the therapeutic effects of cinobufagin in treating melanoma based on network pharmacology, single-cell RNA sequencing data, molecular docking, and molecular dynamics simulation

• Main Authors: Jiansheng Yang (Author), Chunchao Cheng (Author), Zhuolin Wu (Author)
• Formato: Libro
• Publicado: Frontiers Media S.A., 2024-01-01T00:00:00Z.
• Subjects: article
• Acceso en liña: Connect to this object online.

Malignant melanoma is one of the most aggressive of cancers; if not treated early, it can metastasize rapidly. Therefore, drug therapy plays an important role in the treatment of melanoma. Cinobufagin, an active ingredient derived from Venenum bufonis, can inhibit the growth and development of melan...