Development and evaluation of multiparticulate biphasic system for the treatment of circadian diseases

• Main Authors: Sarah Moherdaui Martins (Author), Vinicius Müller (Author), Vanderson Galan (Author), Fabio Pinheiro de Souza (Author), Itamar Francisco Andreazza (Author), Maurício Ferreira da Rosa (Author)
• Format: Book
• Published: Universidade de São Paulo, 2019-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Multiparticulate systems have biopharmaceutical advantages when compared to the monolithic systems, once they allow different patterns of drug release and can be used in different treatments. The aim of the present work was to develop a biphasic controlled release delivery system, using propranolol...