Nitric Oxide/cGMP Signaling Pathway Protects RAW264 Cells Against Nitric Oxide-Induced Apoptosis by Inhibiting the Activation of p38 Mitogen-Activated Protein Kinase

• Auteurs principaux: Yoshioka Yasuhiro (Auteur), Yamamuro Akiko (Auteur), Keun-A Sadaaki (Auteur)
• Format: Livre
• Publié: Elsevier, 2006-01-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Abstract.: Nitric oxide (NO) induces apoptosis in various cells lines, while activation of the NO/cGMP signaling pathway prevents apoptosis induced by diverse stimuli, including NO. Here, we report the cytoprotective mechanisms of the NO/cGMP signaling pathway against NO-induced apoptosis in a mouse...