Xinmailong Modulates Platelet Function and Inhibits Thrombus Formation via the Platelet αIIbβ3-Mediated Signaling Pathway

• Main Authors: Huawei Wang (Author), Yujia Ye (Author), Wen Wan (Author), Luqiao Wang (Author), Ruijie Li (Author), Longjun Li (Author), Lihong Yang (Author), Lai Yang (Author), Yajuan Gu (Author), Ling Dong (Author), Zhaohui Meng (Author)
• Format: Book
• Published: Frontiers Media S.A., 2019-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Xinmailong (XML), a bioactive composite extracted from Periplaneta americana, has been widely used to treat cardiovascular diseases such as congestive heart failure. However, it is unclear whether XML has antiplatelet and antithrombotic effects.Methods: The effects of XML on agonist-indu...