CFTR Modulator Therapy with Lumacaftor/Ivacaftor Alters Plasma Concentrations of Lipid-Soluble Vitamins A and E in Patients with Cystic Fibrosis

• Главные авторы: Olaf Sommerburg (Автор), Susanne Hämmerling (Автор), S. Philipp Schneider (Автор), Jürgen Okun (Автор), Claus-Dieter Langhans (Автор), Patricia Leutz-Schmidt (Автор), Mark O. Wielpütz (Автор), Werner Siems (Автор), Simon Y. Gräber (Автор), Marcus A. Mall (Автор), Mirjam Stahl (Автор)
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• Опубликовано: MDPI AG, 2021-03-01T00:00:00Z.
• Предметы: article
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Rationale: Cystic fibrosis (CF), caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, leads to impaired pancreatic function and therefore reduced intestinal absorption of lipids and fat-soluble vitamins especially in patients with CF developing pancreatic insuf...