Bioorthogonal Chemistry Approach for the Theranostics of GRPR-Expressing Cancers

• Main Authors: Alice D'Onofrio (Author), Francisco Silva (Author), Lurdes Gano (Author), Paula Raposinho (Author), Célia Fernandes (Author), Arkadiusz Sikora (Author), Monika Wyczółkowska (Author), Renata Mikołajczak (Author), Piotr Garnuszek (Author), António Paulo (Author)
• Format: Book
• Published: MDPI AG, 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Several gastrin-releasing peptide receptor (GRPR) antagonists with improved in vivo behavior have been recently developed and tested in the clinic. However, despite the generally mild side effects of peptide receptor radionuclide therapy (PRRT), toxicity has been observed due to high doses delivered...